News release • Brown University • April 13, 2015 • by Kevin Stacey
Researchers from Brown University and the University of Rhode Island have demonstrated a promising new way to increase the effectiveness of radiation in killing cancer cells.
The approach involves gold nanoparticles tethered to acid-seeking compounds called pHLIPs. The pHLIPs (pH low-insertion peptides) home in on high acidity of malignant cells, delivering their nanoparticle passengers straight to the cells’ doorsteps. The nanoparticles then act as tiny antennas, focusing the energy of radiation in the area directly around the cancer cells.
In a paper published in the Proceedings of the National Academy of Sciences, the research team shows that the approach substantially increases the cancer-killing power of radiation in lab tests.
Read through Brown University’s webpage (recommended)